Parkinson disease (PD) is considered a chronic health condition that must be successfully managed over a period of many years. Despite advances in medical management, patients with PD experience a decline in quality of life and physical function over the course of the disease. There is a growing body of evidence revealing the benefits of physical activity, exercise, and rehabilitation in improving participation, decreasing activity limitations, and remediating deficits in body structure and function in people with PD. This course will begin with a review of the underlying neuropathology of PD followed by discussions related to differen-tial diagnosis. An evidence-based approach to the physical therapy examination, diagnosis, prognosis and intervention will be described. This will include, but not be limited to coverage of how varied motor phenotypes (e.g., Freezing of Gait) and PD-related cognitive dysfunction may impact rehabilitation. Responsiveness of commonly used outcome measures will be discussed. The most current re-search supporting potential neuroprotection and neurorestorative effects of exer-cise interventions will be included. Specific elements of treatment will be high-lighted – including overground walking and treadmill training, cardiovascular fitness training, strengthening, balance training, and external cueing. Finally, community-based exercise programs supported by evidence will be discussed.
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